Publicado oct 19, 2018



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Rafael Gustavo Castellanos Garzón

Elkin Rene Barrios Peralta

Alberto Adolfo Vides Velásquez

Maria Francisca Olarte

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Resumen

La intoxicación por acetaminofén es una de las causas más frecuentes de falla hepática aguda fulminante y una de las principales causas de atención en los servicios de urgencias, por intoxicación debida a medicamentos. Recientemente, se han registrado avances en la comprensión fisiopatológica, diagnóstico y tratamiento de esta entidad clínica. Los mecanismos de estrés oxidativo y daño del ADN mitocondrial explican los daños producidos en esta intoxicación. En esta revisión se presentan aspectos referentes a la epidemiología, mecanismos fisiopatológicos, diagnóstico y tratamiento de la intoxicación por acetaminofén.

Keywords

drug overdose; acetaminophen; hepatotoxicitysobredosis de droga; acetaminofén; enfermedad hepática inducida por drogas y medicamentos.

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Cómo citar
Castellanos Garzón, R. G., Barrios Peralta, E. R., Vides Velásquez, A. A., & Olarte, M. F. (2018). Actualización en la comprensión y manejo de la intoxicación por acetaminofén. Universitas Medica, 59(4), 1–11. https://doi.org/10.11144/Javeriana.umed59-4.acet
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